Aim: Renal involvement in malignant patients may lead to kidney disease indirectly for a number of reasons, including direct metastasis or dehydration, hyperuricemia, and tumor lysis syndrome. We tried to evaluate malignant patients who developed kidney disease in our study.
Materials and Methods: This study was performed in malignant patients who applied to the Kahramanmaraş Necip Fazıl City hospital between 2015-2017. Blood urea nitrogen, serum creatinine, uric acid, sodium, potassium, calcium, phosphorus, glucose, complete urine output and hemogram were noted in patients with kidney disease.
Results: A total of 688 cancer patients were included in the study. 53.6% of the patients were female and 46.2% were male. The average age of the patients was found as 60.23 ± 13.25 (21-94). Acute kidney injury was detected in %17,1. When the patients diagnosed with kidney disease were evaluated; serum uric acid levels were higher in 46.2% of patients, calcium-level was low in 7.7% of patients and high in 3.6% of patients, serum potassium level was high in 21.1% of patients, phosphorus level was high in 42.9% and serum sodium level was low in 17.2% of patients. According to Kidney Disease Improve Global Outcomes, an acute renal injury was detected in 42.4% of stage I, 25.4% of stage II, and 32.2% of stage III. Of 118 patients with acute renal injury 33 died.
Conclusion: In our study, the incidence of acute renal injury was 17.1% in cancer patients. The mortality rate was higher in patients with an acute renal injury.
Malignancy, acute renal injury, glomerular filtration rate