E-ISSN 2149-388X | ISSN 2149-0430
 

Original Research 


The Regenerative Effects of Hemostatic Plant Extract in Second Degree Burn Wound

Erhan Cahit Ozcan, Sefa Senol, Yavuz Tokgoz, Tuncay Kuloglu.

Abstract
Introduction: The effects of Ankaferd Blood Stopper (ABS), a hemostatic herbal agent, on wound healing of experimental second degree thermal burn model were analyzed in this study.
Material and Methods: 24 wistar albino rats were used. All rat subjects were divided into 4 equal groups as control, burn control, Ankaferd Blood Stopper and serum physiologic. In all rats except for those in negative control group, second degree thermal burn was formed with metal plates heated on their backs. Biopsies were taken on 0th,7th,14th and 21st days. In tissue samples; they were evaluated in terms of fibroblast increase histopathologically, congestion, inflammatory cell increase and epithelization findings and they were also scored. The values obtained were compared statistically.
Results: No significant difference was observed between groups with regard to fibroblast increase (p>0.05). On the 7th day, congestion values in burn control group was determined higher than ABS group (p<0.005). On 7th day again, inflammatory cell increase in ABS group was identified quite low compared to that of control groups (p<0.005). While a distinct increase was determined in epithelization in ABS group on 7th day, this increase was observed as at medium level in serum physiologic group. There was no increase in epithelization in burn control group. When epithelization findings on 7th day of burn formation were exained, the values in ABS group were determined significantly high compared to other groups (p<005).
Conclusion: Our findings were of supportive quality that ABS has more positive effect on second degree thermal burn healing.

Key words: Burn, burn healing, epithelization, ankaferd


 
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How to Cite this Article
Pubmed Style

Erhan Cahit Ozcan, Sefa Senol, Yavuz Tokgoz, Tuncay Kuloglu. The Regenerative Effects of Hemostatic Plant Extract in Second Degree Burn Wound. Ulutas Med J. 2017; 3(4): 78-84. doi:10.5455/umj.20171108031208


Web Style

Erhan Cahit Ozcan, Sefa Senol, Yavuz Tokgoz, Tuncay Kuloglu. The Regenerative Effects of Hemostatic Plant Extract in Second Degree Burn Wound. http://www.ulutasmedicaljournal.com/?mno=282922 [Access: December 12, 2018]. doi:10.5455/umj.20171108031208


AMA (American Medical Association) Style

Erhan Cahit Ozcan, Sefa Senol, Yavuz Tokgoz, Tuncay Kuloglu. The Regenerative Effects of Hemostatic Plant Extract in Second Degree Burn Wound. Ulutas Med J. 2017; 3(4): 78-84. doi:10.5455/umj.20171108031208



Vancouver/ICMJE Style

Erhan Cahit Ozcan, Sefa Senol, Yavuz Tokgoz, Tuncay Kuloglu. The Regenerative Effects of Hemostatic Plant Extract in Second Degree Burn Wound. Ulutas Med J. (2017), [cited December 12, 2018]; 3(4): 78-84. doi:10.5455/umj.20171108031208



Harvard Style

Erhan Cahit Ozcan, Sefa Senol, Yavuz Tokgoz, Tuncay Kuloglu (2017) The Regenerative Effects of Hemostatic Plant Extract in Second Degree Burn Wound. Ulutas Med J, 3 (4), 78-84. doi:10.5455/umj.20171108031208



Turabian Style

Erhan Cahit Ozcan, Sefa Senol, Yavuz Tokgoz, Tuncay Kuloglu. 2017. The Regenerative Effects of Hemostatic Plant Extract in Second Degree Burn Wound. THE ULUTAS MEDICAL JOURNAL, 3 (4), 78-84. doi:10.5455/umj.20171108031208



Chicago Style

Erhan Cahit Ozcan, Sefa Senol, Yavuz Tokgoz, Tuncay Kuloglu. "The Regenerative Effects of Hemostatic Plant Extract in Second Degree Burn Wound." THE ULUTAS MEDICAL JOURNAL 3 (2017), 78-84. doi:10.5455/umj.20171108031208



MLA (The Modern Language Association) Style

Erhan Cahit Ozcan, Sefa Senol, Yavuz Tokgoz, Tuncay Kuloglu. "The Regenerative Effects of Hemostatic Plant Extract in Second Degree Burn Wound." THE ULUTAS MEDICAL JOURNAL 3.4 (2017), 78-84. Print. doi:10.5455/umj.20171108031208



APA (American Psychological Association) Style

Erhan Cahit Ozcan, Sefa Senol, Yavuz Tokgoz, Tuncay Kuloglu (2017) The Regenerative Effects of Hemostatic Plant Extract in Second Degree Burn Wound. THE ULUTAS MEDICAL JOURNAL, 3 (4), 78-84. doi:10.5455/umj.20171108031208