E-ISSN 2149-388X | ISSN 2149-0430
 

Original Article 


Histopathological Examination of Internal Thoracic Artery and Saphenous Vein in Patients with Diabetes Mellitus: Structural Changes in Grafts Used in Bypass Surgery

Murat Mumtaz Yardimci.

Abstract
Introduction: Epidemiological studies show that cardiovascular mortality is two to three times higher in male gender and three to five times higher in women with diabetes than those without diabetes. In this study, LIMA, which we frequently use in coronary bypass surgery, and the comparison of structural differences, if any, that may affect the saphenous vein, were analyzed with samples taken from diabetic and non-diabetic patients.
Materials and Methods: Twelve diabetic and 12 non-diabetic patients who underwent coronary by-pass between 2003-2004 use of this type were examined. We evaluated the intimal thickness, medial thickness, intima-media ratio, and medial calcification of the biopsies from these grafts used during the operation.
Results: LIMA calcification were calculated as 10,84±0,98” in diabetics and 12±2,15” in the control (p=0.048). When the calcification in saphenous veins was evaluated as a percentage, it was calculated as 7.19±3,47” in the diabetic and 7,95±1,16” in the control (p=0.037). When the LIMA intima thickness was evaluated, it was calculated as 28,75±15,65” and 26,36±24,05” in the control (p=0.044). When the LIMA intima-media ratios were examined, it was calculated as 0.128±0.93” in the diabetic group and 0.117±0.092” in the control (p=0.041). Measurement of saphenous vein intimal thickness was found as 68,05±47,94” in the diabetic group and 66,31±48,07” in the control group (p=0.038). When measured as the medial thickness of the saphenous vein, it was found to be 422,18±131,7” in the diabetic group and 465,6±146,28” in the control (p=0.032).
Conclusion: We could not find any statistically significant difference between the two groups. Since we could not find a significant difference in terms of grafts between the diabetic and control groups, we can only say that postoperative factors cause premature occlusion of grafts in diabetics.

Key words: Internal Thoracic Artery, Saphenous Vein, Diabetes Mellitus, Graft, Bypass Surgery


 
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Pubmed Style

Murat Mumtaz Yardimci. Histopathological Examination of Internal Thoracic Artery and Saphenous Vein in Patients with Diabetes Mellitus: Structural Changes in Grafts Used in Bypass Surgery. Ulutas Med J. 2020; 6(4): 199-207. doi:10.5455/umj.20201030022829


Web Style

Murat Mumtaz Yardimci. Histopathological Examination of Internal Thoracic Artery and Saphenous Vein in Patients with Diabetes Mellitus: Structural Changes in Grafts Used in Bypass Surgery. http://www.ulutasmedicaljournal.com/?mno=21646 [Access: December 30, 2020]. doi:10.5455/umj.20201030022829


AMA (American Medical Association) Style

Murat Mumtaz Yardimci. Histopathological Examination of Internal Thoracic Artery and Saphenous Vein in Patients with Diabetes Mellitus: Structural Changes in Grafts Used in Bypass Surgery. Ulutas Med J. 2020; 6(4): 199-207. doi:10.5455/umj.20201030022829



Vancouver/ICMJE Style

Murat Mumtaz Yardimci. Histopathological Examination of Internal Thoracic Artery and Saphenous Vein in Patients with Diabetes Mellitus: Structural Changes in Grafts Used in Bypass Surgery. Ulutas Med J. (2020), [cited December 30, 2020]; 6(4): 199-207. doi:10.5455/umj.20201030022829



Harvard Style

Murat Mumtaz Yardimci (2020) Histopathological Examination of Internal Thoracic Artery and Saphenous Vein in Patients with Diabetes Mellitus: Structural Changes in Grafts Used in Bypass Surgery. Ulutas Med J, 6 (4), 199-207. doi:10.5455/umj.20201030022829



Turabian Style

Murat Mumtaz Yardimci. 2020. Histopathological Examination of Internal Thoracic Artery and Saphenous Vein in Patients with Diabetes Mellitus: Structural Changes in Grafts Used in Bypass Surgery. THE ULUTAS MEDICAL JOURNAL, 6 (4), 199-207. doi:10.5455/umj.20201030022829



Chicago Style

Murat Mumtaz Yardimci. "Histopathological Examination of Internal Thoracic Artery and Saphenous Vein in Patients with Diabetes Mellitus: Structural Changes in Grafts Used in Bypass Surgery." THE ULUTAS MEDICAL JOURNAL 6 (2020), 199-207. doi:10.5455/umj.20201030022829



MLA (The Modern Language Association) Style

Murat Mumtaz Yardimci. "Histopathological Examination of Internal Thoracic Artery and Saphenous Vein in Patients with Diabetes Mellitus: Structural Changes in Grafts Used in Bypass Surgery." THE ULUTAS MEDICAL JOURNAL 6.4 (2020), 199-207. Print. doi:10.5455/umj.20201030022829



APA (American Psychological Association) Style

Murat Mumtaz Yardimci (2020) Histopathological Examination of Internal Thoracic Artery and Saphenous Vein in Patients with Diabetes Mellitus: Structural Changes in Grafts Used in Bypass Surgery. THE ULUTAS MEDICAL JOURNAL, 6 (4), 199-207. doi:10.5455/umj.20201030022829