E-ISSN 2149-388X | ISSN 2149-0430
 

Original Article 


Is Fasting Necessary in Clinical Biochemical Parameter Assessment?

Berna KUS, Emre DIRICAN, Serdar DOGAN, Abdullah ARPACI.

Abstract
OBJECTIVE: Blood tests are usually requested for patients visiting polyclinics in the morning following fasting. However, as hospitals provide services for 24 hours, blood is collected from patients at every hour of the day, and fasting status cannot be completely ensured. Therefore, in our study, it was aimed to compare the fasting / non-fasting biochemical parameters of individuals.
MATERIALS and METHODS: Our retrospective study examined 18 different most frequently requested blood tests of patients who visited certain polyclinics at our hospital only once as fasting and non-fasting values based on their hours of being requested.
RESULTS: In our study which analyzed a total of 70,352 individuals, statistically significant differences were observed in the fasting/ non-fasting values of ALB, ALT, AST, BUN, CRE, CK, GGT, TP, GLU and Ca. However, when the effect size values were measured for the tests, it was determined that they were not clinically significant (0.006-0.104). In the values of AMYLASE, Pi, T-CHOL, IRON, LIP, TRIG, HDL- CHOL, and ALP, on the other hand, no statistically significant difference was observed.
CONCLUSION: It was observed that there was no noticeable difference between the fasting and non-fasting parameters, and the differences that had a statistical significance did not have a clinical significance. It was concluded that, as long as there is no doubt on routine results, individuals could give blood samples throughout the day with or without fasting.

Key words: Fasting, non-fasting, biochemistry parameters, effect size


 
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How to Cite this Article
Pubmed Style

KUS B, DIRICAN E, DOGAN S, ARPACI A. Is Fasting Necessary in Clinical Biochemical Parameter Assessment?. doi:10.5455/umj.20210325092137online


Web Style

KUS B, DIRICAN E, DOGAN S, ARPACI A. Is Fasting Necessary in Clinical Biochemical Parameter Assessment?. http://www.ulutasmedicaljournal.com/?mno=67604 [Access: April 14, 2021]. doi:10.5455/umj.20210325092137online


AMA (American Medical Association) Style

KUS B, DIRICAN E, DOGAN S, ARPACI A. Is Fasting Necessary in Clinical Biochemical Parameter Assessment?. doi:10.5455/umj.20210325092137online



Vancouver/ICMJE Style

KUS B, DIRICAN E, DOGAN S, ARPACI A. Is Fasting Necessary in Clinical Biochemical Parameter Assessment?. doi:10.5455/umj.20210325092137online



Harvard Style

KUS, B., DIRICAN, . E., DOGAN, . S. & ARPACI, . A. (2021) Is Fasting Necessary in Clinical Biochemical Parameter Assessment?. doi:10.5455/umj.20210325092137online



Turabian Style

KUS, Berna, Emre DIRICAN, Serdar DOGAN, and Abdullah ARPACI. 2021. Is Fasting Necessary in Clinical Biochemical Parameter Assessment?. doi:10.5455/umj.20210325092137online



Chicago Style

KUS, Berna, Emre DIRICAN, Serdar DOGAN, and Abdullah ARPACI. "Is Fasting Necessary in Clinical Biochemical Parameter Assessment?." doi:10.5455/umj.20210325092137online



MLA (The Modern Language Association) Style

KUS, Berna, Emre DIRICAN, Serdar DOGAN, and Abdullah ARPACI. "Is Fasting Necessary in Clinical Biochemical Parameter Assessment?." doi:10.5455/umj.20210325092137online



APA (American Psychological Association) Style

KUS, B., DIRICAN, . E., DOGAN, . S. & ARPACI, . A. (2021) Is Fasting Necessary in Clinical Biochemical Parameter Assessment?. doi:10.5455/umj.20210325092137online