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Evaluation of Plasma Selenium, Zinc and Malondialdehyde Levels in Newly Diagnosed Preeclamptic Women at A Teaching Hospital

Obianuju Uchenna Ilechukwu, Jude Anaelechi Onuegbu, Japhet Madu Olisekodiaka, Chikaodili Nwando Obi-Ezeani.


Cited By:2

Abstract
Introduction: Preeclampsia is a clinical condition unique to humans which forms a major part of hypertensive disorders in pregnancy. Although its exact etiology remains unknown, an imbalance between lipid peroxides and antioxidants is implicated. The study aimed to evaluate plasma selenium, zinc, and malondialdehyde (MDA) levels in newly diagnosed preeclamptic women attending antenatal visits at Chukwuemeka Odumegwu Ojukwu University Teaching Hospital (COOUTH), Awka in Anambra State.
Materials and Methods: A total of 81 female participants were recruited and grouped into three (A, B, and C) comprising 21 newly diagnosed preeclamptic women, 30 healthy pregnant control, and 30 non-pregnant control participants respectively.
Results: The newly diagnosed preeclamptics had significantly lower plasma selenium levels when compared with the healthy pregnant and non-pregnant controls (p<0.05). The plasma zinc level in the preeclamptics did not differ significantly from the level in healthy pregnant women (p>0.05), it was however significantly lower in the preeclamptics and healthy pregnant women when compared with the non-pregnant women (p<0.05). Plasma MDA level was significantly elevated in the preeclamptics compared to the healthy pregnant and non-pregnant control participants (p<0.05).
Conclusion: Newly diagnosed preeclamptics have lower plasma selenium and zinc levels with higher plasma MDA levels, and additional sources of these micronutrients may be required.

Key words: Preeclampsia, Pregnancy, Selenium, Zinc, Malondialdehyde


 
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How to Cite this Article
Pubmed Style

Ilechukwu OU, Onuegbu JA, Olisekodiaka JM, Obi-Ezeani CN. Evaluation of Plasma Selenium, Zinc and Malondialdehyde Levels in Newly Diagnosed Preeclamptic Women at A Teaching Hospital. Ulutas Med J. 2021; 7(2): 86-91. doi:10.5455/umj.20210422011242

Web Style

Ilechukwu OU, Onuegbu JA, Olisekodiaka JM, Obi-Ezeani CN. Evaluation of Plasma Selenium, Zinc and Malondialdehyde Levels in Newly Diagnosed Preeclamptic Women at A Teaching Hospital. https://www.ulutasmedicaljournal.com/?mno=75583 [Access: March 06, 2024]. doi:10.5455/umj.20210422011242

AMA (American Medical Association) Style

Ilechukwu OU, Onuegbu JA, Olisekodiaka JM, Obi-Ezeani CN. Evaluation of Plasma Selenium, Zinc and Malondialdehyde Levels in Newly Diagnosed Preeclamptic Women at A Teaching Hospital. Ulutas Med J. 2021; 7(2): 86-91. doi:10.5455/umj.20210422011242


Vancouver/ICMJE Style

Ilechukwu OU, Onuegbu JA, Olisekodiaka JM, Obi-Ezeani CN. Evaluation of Plasma Selenium, Zinc and Malondialdehyde Levels in Newly Diagnosed Preeclamptic Women at A Teaching Hospital. Ulutas Med J. (2021), [cited March 06, 2024]; 7(2): 86-91. doi:10.5455/umj.20210422011242


Harvard Style

Ilechukwu, O. U., Onuegbu, . J. A., Olisekodiaka, . J. M. & Obi-Ezeani, . C. N. (2021) Evaluation of Plasma Selenium, Zinc and Malondialdehyde Levels in Newly Diagnosed Preeclamptic Women at A Teaching Hospital. Ulutas Med J, 7 (2), 86-91. doi:10.5455/umj.20210422011242


Turabian Style

Ilechukwu, Obianuju Uchenna, Jude Anaelechi Onuegbu, Japhet Madu Olisekodiaka, and Chikaodili Nwando Obi-Ezeani. 2021. Evaluation of Plasma Selenium, Zinc and Malondialdehyde Levels in Newly Diagnosed Preeclamptic Women at A Teaching Hospital. THE ULUTAS MEDICAL JOURNAL, 7 (2), 86-91. doi:10.5455/umj.20210422011242


Chicago Style

Ilechukwu, Obianuju Uchenna, Jude Anaelechi Onuegbu, Japhet Madu Olisekodiaka, and Chikaodili Nwando Obi-Ezeani. "Evaluation of Plasma Selenium, Zinc and Malondialdehyde Levels in Newly Diagnosed Preeclamptic Women at A Teaching Hospital." THE ULUTAS MEDICAL JOURNAL 7 (2021), 86-91. doi:10.5455/umj.20210422011242


MLA (The Modern Language Association) Style

Ilechukwu, Obianuju Uchenna, Jude Anaelechi Onuegbu, Japhet Madu Olisekodiaka, and Chikaodili Nwando Obi-Ezeani. "Evaluation of Plasma Selenium, Zinc and Malondialdehyde Levels in Newly Diagnosed Preeclamptic Women at A Teaching Hospital." THE ULUTAS MEDICAL JOURNAL 7.2 (2021), 86-91. Print. doi:10.5455/umj.20210422011242


APA (American Psychological Association) Style

Ilechukwu, O. U., Onuegbu, . J. A., Olisekodiaka, . J. M. & Obi-Ezeani, . C. N. (2021) Evaluation of Plasma Selenium, Zinc and Malondialdehyde Levels in Newly Diagnosed Preeclamptic Women at A Teaching Hospital. THE ULUTAS MEDICAL JOURNAL, 7 (2), 86-91. doi:10.5455/umj.20210422011242


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