E-ISSN 2149-388X | ISSN 2149-0430
 

Original Article 


The Relationship between Serum Ferritin Level and Insulin Resistance in Metabolic Syndrome

Ugur Fahri Yurekli, Riza Altunbas.

Abstract
Introduction: Insulin resistance and metabolic syndrome (MetS) are risk factors for diabetes mellitus, and their prevalence is increasing. Ferritin has emerged as a biomarker of low-grade inflammation in addition to its role in iron metabolism. The study aims to determine the correlation between ferritin and insulin resistance (IR) in MetS.
Materials and Methods: In this study, ferritin, glucose (fasting), and HOMA-IR were measured from serum samples obtained from 98 MetS patients and 100 healthy volunteers. Serum ferritin, glucose, insulin, and HOMA-IR results were compared between the MetS and the control group. Correlation analysis was performed between ferritin and HOMA-IR in control and MetS patients.
Results: Serum ferritin (Control: 93,9±30,13; MetS:200±57,31 ng/ml), glucose (Control: 100,9±11,86, 123,9±21,52 ng/dl), insulin (Control: 4,11±2,57; MetS:15,99±5,71 µU/ml) and HOMA-IR (Control: 1,04±0,74; MetS:5,07±2,33) revealed to be higher in MetS compared to control. The correlation between serum ferritin level and HOMA-IR in MetS patients was revealed. This correlation was not found in the control group.
Conclusion: In MetS, high serum ferritin level increases insulin resistance. While the positive correlation of ferritin with insulin resistance occurs at high ferritin levels, this is not observed at low ferritin levels.

Key words: Metabolic syndrome, glucose, insulin, HOMA-IR


 
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How to Cite this Article
Pubmed Style

Yurekli UF, Altunbas R. The Relationship between Serum Ferritin Level and Insulin Resistance in Metabolic Syndrome. Ulutas Med J. 2023; 9(1): 30-34. doi:10.5455/umj.20230119123818


Web Style

Yurekli UF, Altunbas R. The Relationship between Serum Ferritin Level and Insulin Resistance in Metabolic Syndrome. https://www.ulutasmedicaljournal.com/?mno=141071 [Access: December 05, 2023]. doi:10.5455/umj.20230119123818


AMA (American Medical Association) Style

Yurekli UF, Altunbas R. The Relationship between Serum Ferritin Level and Insulin Resistance in Metabolic Syndrome. Ulutas Med J. 2023; 9(1): 30-34. doi:10.5455/umj.20230119123818



Vancouver/ICMJE Style

Yurekli UF, Altunbas R. The Relationship between Serum Ferritin Level and Insulin Resistance in Metabolic Syndrome. Ulutas Med J. (2023), [cited December 05, 2023]; 9(1): 30-34. doi:10.5455/umj.20230119123818



Harvard Style

Yurekli, U. F. & Altunbas, . R. (2023) The Relationship between Serum Ferritin Level and Insulin Resistance in Metabolic Syndrome. Ulutas Med J, 9 (1), 30-34. doi:10.5455/umj.20230119123818



Turabian Style

Yurekli, Ugur Fahri, and Riza Altunbas. 2023. The Relationship between Serum Ferritin Level and Insulin Resistance in Metabolic Syndrome. THE ULUTAS MEDICAL JOURNAL, 9 (1), 30-34. doi:10.5455/umj.20230119123818



Chicago Style

Yurekli, Ugur Fahri, and Riza Altunbas. "The Relationship between Serum Ferritin Level and Insulin Resistance in Metabolic Syndrome." THE ULUTAS MEDICAL JOURNAL 9 (2023), 30-34. doi:10.5455/umj.20230119123818



MLA (The Modern Language Association) Style

Yurekli, Ugur Fahri, and Riza Altunbas. "The Relationship between Serum Ferritin Level and Insulin Resistance in Metabolic Syndrome." THE ULUTAS MEDICAL JOURNAL 9.1 (2023), 30-34. Print. doi:10.5455/umj.20230119123818



APA (American Psychological Association) Style

Yurekli, U. F. & Altunbas, . R. (2023) The Relationship between Serum Ferritin Level and Insulin Resistance in Metabolic Syndrome. THE ULUTAS MEDICAL JOURNAL, 9 (1), 30-34. doi:10.5455/umj.20230119123818