E-ISSN 2149-388X | ISSN 2149-0430
 

Original Article 


Relationship between COVID-19 Infection and Buerger's Disease-Related Amputations

Mehmet Yilmaz, Nevzat Gonder.

Abstract
Introduction: Thromboangiitis obliterans (TAO) or Buerger's disease is a non-atherosclerotic, inflammatory arteritis involving small and medium-sized arteries and veins of the extremities, often causing gangrene and scarring. Coronavirus disease (COVID-19) may predispose to both arterial and venous thromboembolic complications. This study examined the relationship between COVID-19 infection and Buerger's disease-related amputations.
Materials and Methods: Between January 2018 and July 2023, 54 patients who applied to our clinic for Buerger's disease and were followed up and treated were analyzed retrospectively. Follow-up information, demographic data of patients (age, gender, body mass index (BMI), education status), when they were diagnosed, amount of smoking (pack/year), all treatments applied for Buerger's disease (Pre-Covid – Covid period – Covid Afterwards), presence or absence of limb amputation, continued smoking, medications, cardiovascular risk factors, Charlson Comorbidity Index (CCI), Venous Thromboembolic Event (Pulmonary Embolism), Covid-19 History and vaccination information were noted.
Results: The mean age of 54 patients included in the study was 38.1 (27-49), all male. The mean smoking rate was 32 (16 - 60) packs/year, and the mean exposure to the SARS-CoV-2 virus was 1.22 (0-4) times. There was a significant correlation between major amputations due to Buerger's disease and age, severity of COVID-19 disease, and systemic hypertension (p<0.005). Major amputation rates increased during the period of COVID-19 disease (p<0.05).
Conclusion: We found a statistically significant increase in major amputations as the exposure to the virus or the severity of the COVID-19 disease increased. We also observed a significant increase in major amputation rates in the presence of systemic hypertension. The presence of COVID-19 disease and hypertension should be considered when planning treatment to prevent amputation in Buerger's patients.

Key words: Buerger Disease, COVID-19 Disease, Amputation, Hypertension


 
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How to Cite this Article
Pubmed Style

Yilmaz M, Gonder N. Relationship between COVID-19 Infection and Buerger's Disease-Related Amputations. Ulutas Med J. 2023; 9(3): 193-201. doi:10.5455/umj.20230903113816


Web Style

Yilmaz M, Gonder N. Relationship between COVID-19 Infection and Buerger's Disease-Related Amputations. https://www.ulutasmedicaljournal.com/?mno=168118 [Access: December 05, 2023]. doi:10.5455/umj.20230903113816


AMA (American Medical Association) Style

Yilmaz M, Gonder N. Relationship between COVID-19 Infection and Buerger's Disease-Related Amputations. Ulutas Med J. 2023; 9(3): 193-201. doi:10.5455/umj.20230903113816



Vancouver/ICMJE Style

Yilmaz M, Gonder N. Relationship between COVID-19 Infection and Buerger's Disease-Related Amputations. Ulutas Med J. (2023), [cited December 05, 2023]; 9(3): 193-201. doi:10.5455/umj.20230903113816



Harvard Style

Yilmaz, M. & Gonder, . N. (2023) Relationship between COVID-19 Infection and Buerger's Disease-Related Amputations. Ulutas Med J, 9 (3), 193-201. doi:10.5455/umj.20230903113816



Turabian Style

Yilmaz, Mehmet, and Nevzat Gonder. 2023. Relationship between COVID-19 Infection and Buerger's Disease-Related Amputations. THE ULUTAS MEDICAL JOURNAL, 9 (3), 193-201. doi:10.5455/umj.20230903113816



Chicago Style

Yilmaz, Mehmet, and Nevzat Gonder. "Relationship between COVID-19 Infection and Buerger's Disease-Related Amputations." THE ULUTAS MEDICAL JOURNAL 9 (2023), 193-201. doi:10.5455/umj.20230903113816



MLA (The Modern Language Association) Style

Yilmaz, Mehmet, and Nevzat Gonder. "Relationship between COVID-19 Infection and Buerger's Disease-Related Amputations." THE ULUTAS MEDICAL JOURNAL 9.3 (2023), 193-201. Print. doi:10.5455/umj.20230903113816



APA (American Psychological Association) Style

Yilmaz, M. & Gonder, . N. (2023) Relationship between COVID-19 Infection and Buerger's Disease-Related Amputations. THE ULUTAS MEDICAL JOURNAL, 9 (3), 193-201. doi:10.5455/umj.20230903113816