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Ferritin Lymphocyte Ratio and D-dimer C-Reactive Protein Ratio as Diagnostic Parameters in Pre-COVID-19 Healthy Individuals

Ibrahim Koc, Serdar Dogan.


Abstract
Introduction: The gold standard diagnostic tool for COVID-19 is real‐time reverse‐transcription polymerase chain reaction (PCR) which is not available in every healthcare institution. There is a need for faster, cheaper, and available tests. This study aimed to determine if eosinophil levels, neutrophil-lymphocyte ratio (NLR), ferritin C-reactive protein (CRP) ratio (FCR), and D-dimer to CRP ratio (DCR) can be used as biomarkers in the early diagnosis of pre-COVID-19 healthy individuals.
Materials and Methods: 289 previously healthy COVID-19 patients and 152 SARS-CoV-2 PCR negative healthy controls were included in the study. Two patient groups were compared by examining the parameters such as white blood count (WBC), neutrophil, monocyte, eosinophil, and red blood cell distribution width (RDW) obtained at the time of hospital admission before using any kind of medication.
Results: Eosinophil levels, FLR, DCR, and NLR remained significantly lower, whereas DCR, FLR, and CRP lymphocyte ratio (CLR) were found to be higher in the COVID-19 group.
Conclusion: High levels of RDW, FLR, and CLR whereas low levels of WBC, monocyte, NLR, FCR, and DCR may predict COVID-19 in patients with no comorbidities.

Key words: Ferritin lymphocyte ratio, monocyte lymphocyte ratio, COVID-19


 
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How to Cite this Article
Pubmed Style

Koc I, Dogan S. Ferritin Lymphocyte Ratio and D-dimer C-Reactive Protein Ratio as Diagnostic Parameters in Pre-COVID-19 Healthy Individuals. Ulutas Med J. 2022; 8(1): 51-57. doi:10.5455/umj.20211204105007

Web Style

Koc I, Dogan S. Ferritin Lymphocyte Ratio and D-dimer C-Reactive Protein Ratio as Diagnostic Parameters in Pre-COVID-19 Healthy Individuals. https://www.ulutasmedicaljournal.com/?mno=39584 [Access: March 15, 2025]. doi:10.5455/umj.20211204105007

AMA (American Medical Association) Style

Koc I, Dogan S. Ferritin Lymphocyte Ratio and D-dimer C-Reactive Protein Ratio as Diagnostic Parameters in Pre-COVID-19 Healthy Individuals. Ulutas Med J. 2022; 8(1): 51-57. doi:10.5455/umj.20211204105007


Vancouver/ICMJE Style

Koc I, Dogan S. Ferritin Lymphocyte Ratio and D-dimer C-Reactive Protein Ratio as Diagnostic Parameters in Pre-COVID-19 Healthy Individuals. Ulutas Med J. (2022), [cited March 15, 2025]; 8(1): 51-57. doi:10.5455/umj.20211204105007


Harvard Style

Koc, I. & Dogan, . S. (2022) Ferritin Lymphocyte Ratio and D-dimer C-Reactive Protein Ratio as Diagnostic Parameters in Pre-COVID-19 Healthy Individuals. Ulutas Med J, 8 (1), 51-57. doi:10.5455/umj.20211204105007


Turabian Style

Koc, Ibrahim, and Serdar Dogan. 2022. Ferritin Lymphocyte Ratio and D-dimer C-Reactive Protein Ratio as Diagnostic Parameters in Pre-COVID-19 Healthy Individuals. THE ULUTAS MEDICAL JOURNAL, 8 (1), 51-57. doi:10.5455/umj.20211204105007


Chicago Style

Koc, Ibrahim, and Serdar Dogan. "Ferritin Lymphocyte Ratio and D-dimer C-Reactive Protein Ratio as Diagnostic Parameters in Pre-COVID-19 Healthy Individuals." THE ULUTAS MEDICAL JOURNAL 8 (2022), 51-57. doi:10.5455/umj.20211204105007


MLA (The Modern Language Association) Style

Koc, Ibrahim, and Serdar Dogan. "Ferritin Lymphocyte Ratio and D-dimer C-Reactive Protein Ratio as Diagnostic Parameters in Pre-COVID-19 Healthy Individuals." THE ULUTAS MEDICAL JOURNAL 8.1 (2022), 51-57. Print. doi:10.5455/umj.20211204105007


APA (American Psychological Association) Style

Koc, I. & Dogan, . S. (2022) Ferritin Lymphocyte Ratio and D-dimer C-Reactive Protein Ratio as Diagnostic Parameters in Pre-COVID-19 Healthy Individuals. THE ULUTAS MEDICAL JOURNAL, 8 (1), 51-57. doi:10.5455/umj.20211204105007


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