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2023, Vol: 9, Issue: 1
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Changing of Hemoglobin A1c Affects Mean Platelet Volume in Type-2 Diabetes Mellitus

Huseyin Kurt, Davut Demirkiran.

Cited By: 6

Abstract
Background: Mean platelet volume (MPV) level is known to increase in diabetes mellitus (DM).
Objective: In this study, the first aim is to examine whether there is a correlation between MPV and hemoglobin A1c (HbA1c) and fasting plasma glucose (FPG). The second aim is to investigate whether a correlation exists between MPV and HbA1c and FPG changes after treatment
Method: In the study, we examined baseline and final HbA1c, MPV and FPGA values of 343 patients. Including the study group (SG) consisted of 169 patients with diabetes whose HbA1c levels decreased %1 and the control group involving 174 patients whose HbA1c levels did not change.
Results: Similar to CG, HbA1c level of SG decreased to 7.58, and MPV level reduced to 8.68. There existed a positive correlation between MPV and HbA1c levels (r=154; p<0.005). Additionally, positive correlation was found between MPV and HbA1c changes (r=216; p=0.005), and MPV and FPG changes (r=245; p=0.001) in SG. Moreover, there was a positive correlation between MPV and HbA1c changes (r=306; p<0.005), and MPV and FPG changes (r=306; p<0.005) in patients underwent insulin treatment.
Conclusion: The change in HbA1c level is similar to MPV level change. The effect of insulin therapy on MPV is significant.

Key words: Mean platelet volume, diabetes mellitus, hemoglobin A1c, fasting plasma glucose. 


 
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How to Cite this Article
Pubmed Style

Huseyin Kurt, Davut Demirkiran. Changing of Hemoglobin A1c Affects Mean Platelet Volume in Type-2 Diabetes Mellitus. Ulutas Med J. 2016; 2(1): 27-35. doi:10.5455/umj.20160211122820

Web Style

Huseyin Kurt, Davut Demirkiran. Changing of Hemoglobin A1c Affects Mean Platelet Volume in Type-2 Diabetes Mellitus. https://www.ulutasmedicaljournal.com/?mno=215692 [Access: March 25, 2023]. doi:10.5455/umj.20160211122820

AMA (American Medical Association) Style

Huseyin Kurt, Davut Demirkiran. Changing of Hemoglobin A1c Affects Mean Platelet Volume in Type-2 Diabetes Mellitus. Ulutas Med J. 2016; 2(1): 27-35. doi:10.5455/umj.20160211122820


Vancouver/ICMJE Style

Huseyin Kurt, Davut Demirkiran. Changing of Hemoglobin A1c Affects Mean Platelet Volume in Type-2 Diabetes Mellitus. Ulutas Med J. (2016), [cited March 25, 2023]; 2(1): 27-35. doi:10.5455/umj.20160211122820


Harvard Style

Huseyin Kurt, Davut Demirkiran (2016) Changing of Hemoglobin A1c Affects Mean Platelet Volume in Type-2 Diabetes Mellitus. Ulutas Med J, 2 (1), 27-35. doi:10.5455/umj.20160211122820


Turabian Style

Huseyin Kurt, Davut Demirkiran. 2016. Changing of Hemoglobin A1c Affects Mean Platelet Volume in Type-2 Diabetes Mellitus. THE ULUTAS MEDICAL JOURNAL, 2 (1), 27-35. doi:10.5455/umj.20160211122820


Chicago Style

Huseyin Kurt, Davut Demirkiran. "Changing of Hemoglobin A1c Affects Mean Platelet Volume in Type-2 Diabetes Mellitus." THE ULUTAS MEDICAL JOURNAL 2 (2016), 27-35. doi:10.5455/umj.20160211122820


MLA (The Modern Language Association) Style

Huseyin Kurt, Davut Demirkiran. "Changing of Hemoglobin A1c Affects Mean Platelet Volume in Type-2 Diabetes Mellitus." THE ULUTAS MEDICAL JOURNAL 2.1 (2016), 27-35. Print. doi:10.5455/umj.20160211122820


APA (American Psychological Association) Style

Huseyin Kurt, Davut Demirkiran (2016) Changing of Hemoglobin A1c Affects Mean Platelet Volume in Type-2 Diabetes Mellitus. THE ULUTAS MEDICAL JOURNAL, 2 (1), 27-35. doi:10.5455/umj.20160211122820


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